Long-Acting Injectables (LAIs)

At Animo Sano Psychiatry, we recognize the significant role that Long-Acting Injectables (LAIs) play for long-term stability and well-being . Our Long-Acting Injectables (LAIs) service provides a reliable, effective alternative to daily oral medications, ensuring consistent medication levels and improved outcomes.

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Long-Acting Injectables (LAIs) at Animo Sano Psychiatry

Long-Acting Injectables, or LAIs, are a type of medication that helps manage serious mental health conditions like psychosis, schizophrenia, bipolar disorder, and substance use disorders. Instead of taking oral medications every day, people get an injection once every few weeks or months. This treatment option simplifies medication management, providing peace of mind and greater stability. By maintaining steady medication levels, LAIs help minimize symptoms and support long-term well-being.

At Animo Sano Psychiatry our team will work  closely with you to determine if Long-Acting Injections are the right fit for your treatment plan. Through regular monitoring and open communication, we can determine if this approach meets your unique needs and helps you thrive.  

Reasons to consider LAIs

Improved Adherence: Reduces the need for daily medication reminders.

Consistent Medication Levels: Helps maintain stability and prevent relapse.  

Fewer Fluctuations: Minimizes mood swings and symptom variations.

Convenience: Administered in-office for easy management.

What to Expect with Long-Acting Injectables (LAIs)

1. Initial Consultation

  • Your provider will conduct a detailed discussion about your symptoms, treatment history, and goals to determine if LAIs are suitable for you.
  • They will provide a comprehensive explanation of how the medication works, potential side effects, and the injection schedule.
  • You will also first try an oral form of the medication to ensure tolerability and symptom management prior to switching to a long acting injectable option. 

2. First Injection

  • The injection is typically administered into the upper arm, thigh, or gluteal muscle.
  • Depending on the medication prescribed, you might require an initial oral dose to establish effectiveness before fully transitioning to the injectable medication.
  • The injection process is generally quick, lasting only a few minutes.

3. Follow-Up Schedule

  • Injections are administered at intervals ranging from a few weeks to a few months, depending on the specific medication.
  • Your provider will schedule regular follow-up appointments to monitor the medication’s effectiveness and address any potential side effects.

4. Minimal Daily Medication Management

  • With LAIs, you won’t need to remember to take daily pills.
  • This ensures consistent medication levels, which helps prevent symptom relapses.

5. Ongoing Support

  • If you experience any side effects or have concerns, our team is readily available to adjust your treatment plan.
  • Regular check-ins will be scheduled to ensure the medication continues to meet your needs effectively.

Clinical Advantages of LAIs: Evidence-Based Benefits

Research and clinical practice consistently demonstrate the significant positive impact of Long-Acting I njectables (LAIs) on treatment outcomes for individuals with serious mental illnesses. Key benefits supported by scientific evidence include:

  • Substantial Reduction in Relapse Rates – LAIs ensure consistent therapeutic medication levels, significantly lowering the risk of relapse compared to oral medications. Clinical studies have shown a notable decrease in hospitalization rates among patients using LAIs, highlighting their effectiveness in maintaining long-term stability.
  • Enhanced Symptom Stabilization – LAIs provide a steady release of medication, minimizing fluctuations in drug levels and resulting in more stable symptom control. This helps prevent the occurrence of mood swings, psychotic episodes, and other symptoms associated with inconsistent medication levels.
  • Significant Decrease in Hospitalization Rates – Studies indicate that patients using LAIs experience a substantial reduction (up to 30%) in hospitalization rates due to symptom exacerbation. This underscores the effectiveness of LAIs in preventing acute episodes and promoting long-term stability.
  • Improved Patient Quality of Life – Patients often report a greater sense of stability, fewer disruptions in their daily lives, and increased confidence in their treatment plans when using LAIs. This contributes to an enhanced overall quality of life and improved functional outcomes.

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Key Coverage Considerations

Insurance coverage for Long-Acting Injectables (LAIs) varies depending on the medication, diagnosis, and individual insurance plan. Many commercial insurance providers, Medicare, and Medicaid cover LAIs, but prior authorization is often required

  • LAIs for FDA-approved conditions like schizophrenia, bipolar disorder, and substance use disorders are often covered by major insurance plans.
  • Prior authorization is frequently needed, requiring providers to demonstrate medical necessity for approval.
  • Out-of-pocket costs, including copays, differ between plans; some may necessitate step therapy before LAI approval.
  • Financial assistance options, such as patient assistance programs and manufacturer coupons, may be available to help reduce costs for eligible individuals.

Checking your LAI coverage is simple

  • Contact your insurance provider to confirm formulary coverage and prior authorization (PA) requirements.
  • Our team is available to assist with the prior authorization process and any necessary appeals.
  • Inquire about manufacturer financial assistance programs if your insurance does not fully cover the cost.

Who Might Benefit?

LAIs are highly beneficial for those experiencing frequent relapses or hospitalizations due to medication non-compliance, as they ensure steady therapeutic drug levels. Additionally, individuals who prefer a more structured and predictable treatment regimen, may find LAIs to be a suitable option.
If you’re exploring alternative treatment options and believe LAIs might align with your needs, we encourage you to contact our team for a personalized consultation. 

Possible Side Effects

It’s crucial to discuss potential side effects with your provider before starting LAI treatment. Common possibilities include:

  • Injection site reactions like pain or redness are common but usually mild.
  • Weight changes or metabolic effects can occur; discuss concerns with your provider.
  • Movement-related side effects like restlessness are possible but typically manageable.
  • Report any severe or unusual symptoms to your provider immediately.

Steps To Get Started

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Step 1

Schedule an evaluation with a provider.

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Step 2

Insurance verification and prior authorization (if needed).

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Step 3

Administration appointment and follow-up schedule.

Is an LAI Right for You?

If you’re struggling with medication adherence or recurrent symptoms, LAIs could be a significant improvement. Contact us to discuss your options.

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